Search on: NODAL SIGNALING LIGANDS 
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Descriptor English:   Nodal Signaling Ligands 
Descriptor Spanish:   Ligandos de Señalización Nodal 
Descriptor Portuguese:   Ligantes da Sinalização Nodal 
Tree Number:   D12.644.276.954.550
D12.776.467.942.550
D23.529.942.550
Definition English:   Members of the transforming growth factor superfamily that play a role in pattern formation and differentiation during the pregastrulation and GASTRULATION stages of chordate development. Several nodal signaling ligands are specifically involved in the genesis of left-right asymmetry during development. The protein group is named after a critical region of the vertebrate embryo PRIMITIVE STREAK referred to as HENSEN'S NODE. 
History Note English:   2009 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   53145 
Unique Identifier:   D055456 

Occurrence in VHL:
 

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